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Lapatinib-d7 ditosylate Size:Contact [email protected] for quotation JX06 (1-10 μM) increases glucose

SKU: 94755322813

4.7
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Description

JX06 (1-10 μM) increases glucose uptake and intracellular ATP level and reduces aerobic glycolysis determined by the lactate production in A549 cells

thereby increasing the synaptic concentration of norepinephrine in the central nervous system and subsequently prolonging the action of norepinephrine on central receptors

0 nM) and a very low affinity for the A1 receptors (Ki>10

Solubility: DMSO : 125 mg/mL (780

Formula: C53H82O24

Lapatinib-d7 ditosylate Size:Contact [email protected] for quotation JX06 (1-10 μM) increases glucoseLapatinib d7 (GW572016 d7) ditosylate is the deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent inhibitor of the ErbB 2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB 2 of 10. 2 and 9. 8 nM, respectively. Product information CAS Number: 1009307 24 7 Molecular Weight: 760. 30 Formula: C36H34ClFN4O7S2 Chemical Name: 4 methylbenzene 1 sulfonic acid; N {3 chloro 4 [(3 fluorophenyl)methoxy]phenyl} 6 [5 ({[2

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