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25 mg/kg/day
PubMed PMID: 17312463
Chemical Name: sodium hydrate hydrogen {1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl}phosphonate
Tetrodotoxin is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (NaV) channels
InChi: InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21
AMG 487 - CAS# 473719-41-4 Catalog No.:M10194-2 25 mg/kg/dayAMG 487 is a potent and selective antagonist of chemokine (C X C motif) receptor 3 (CXCR3) with IC50 values of 8nM and 8. 2nM for I IP 10 and I ITAC, respectively. AMG 487 prevents the chemokines I IP 10 and I ITAC from binding to CXCR3. In the cellular assays, AMG 487 inhibits CXCR3 mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I IP 10, I ITAC and MIG, respectively. Product information CAS Number: 473719 41 4 Molecular Weight:
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