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33)18(10)29/h4-6
InChiKey: UYGZODVVDUIDDQ-UHFFFAOYSA-N
3-thiazol-2-yl]carbamoyl}-1H-indol-1-yl)acetic acid
3 days) inhibits the BRAF-mutant human melanoma and colorectal cancer cells proliferation with a EC50 range of 1-10 nM
1 h) strongly and significantly increases ERK1/2 phosphorylation in Jurkat E6
Mc-Val-Cit-PAB-Cl Catalog No.:M25483-C 33)18(10)29/h4-6Mc Val Cit PAB Cl is a cleavable ADC linker. Mc Val Cit PAB Cl can be used to conjugate MMAE and antibody to form antibody MC vc MMAE (e. g., anti CD22 MC VC PABC MMAE with IC50s of 3. 3 and 0. 95 nM for BJAB and WSU cell lines in cytotoxicity assay). Product information CAS Number: 1639351 92 0 Molecular Weight: 591. 10 Formula: C28H39ClN6O6 Chemical Name: N [(1S) 1 {[(1S) 4 (carbamoylamino) 1 {[4 (chloromethyl)phenyl]carbamoyl}butyl]carbamoyl} 2
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