PF-670462 is a potent inhibitor of Wnt/β-catenin signaling
DAF-FM fluorescence can be detected by any instrument that can detect fluorescein
CAS Number: 1050480-30-2
It is showed that tanshinones significantly inhibited A549 proliferation and Isocryptotanshinone (ICTS) exhibits the strongest activity
Chemical Name: (9aS)-3-tert-butyl-9a-(2-phenoxyethyl)-3H
Isoalantolactone tagonist G TFA PF-670462 is a potent inhibitorIsoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia. Isoalantolactone is an apoptosis inducer, which also acts as an alkylating