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α2b- and α2c-adrenergic
3H2O/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7
2-diphenylacetamide
Molecular Weight: 1486
The specific binding of [125I]-angiotensin II to VSMC is inhibited by EXP3174 with an IC50 of 1
Argatroban SK-3 inhibitor 1 α2b- and α2c-adrenergicArgatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin induced thrombocytopenia (HIT). Argatroban is a direct thrombin inhibitor that reversibly binds to the thrombin active site. Argatroban exerts its anticoagulant effects by inhibiting thrombin catalyzed or induced reactions, including fibrin formation; activation of coagulation factors