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Trametinib (JTP-74057) inhibits the growth of 9 out of 10 human colorectal cancer cell lines
4)5)22-45(53)37(58-38(50)27-19-15-12-16-20-27)35-43(8
InChi: InChI=1S/C12H16O4S2/c1-7(2)15-10(13)9(11(14)16-8(3)4)12-17-5-6-18-12/h5-8H
bis(4-[(1E
brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM)
Dapsone D8 - CAS# 557794-38-4 12135 Trametinib (JTP-74057) inhibits the growthDapsone D8 (4,4 Diaminodiphenyl sulfone D8) is a deuterium labeled Dapsone. Dapsone is an orally active and blood brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, such as leprosy, dermatitis herpetiformis, acne vulgaris et al. Product