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CAS Number: 1158838-45-9
FH535 shows toxic effects on 12 carcinoma cell lines expressing wnt/β-catenin pathway[1]
Alprostadil is a drug used in the continuous treatment of erectile dysfunction and has vasodilatory properties
InChi: InChI=1S/C22H24O6/c1-11-5-13-7-15-19(27-9-25-15)21(23-3)17(13)18-14(6-12(11)2)8-16-20(22(18)24-4)28-10-26-16/h7-8
Smiles: COC1=CC=C(CNC2=NC(=NC=C2C(=O)NCC2N=CC=CN=2)N2CCC[C@H]2CO)C=C1Cl
Palovarotene - CAS# 410528-02-8 Size:Solid 10 mg CAS Number: 1158838-45-9Palovarotene, also known as RO 3300074 and R 667, is a highly selective retinoic acid receptor gamma (RAR ) agonist that is under investigation as a potential treatment for emphysema. Phase I clinical trials of palovarotene in patients with emphysema demonstrated that the drug is well tolerated, with improvements observed in markers of emphysema progression. Emphysema is characterized by the destruction of alveoli and alveolar ducts within the lungs.
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