BACE1-IN-2 255ipexide including the breast cancer cell

including the breast cancer cell lines MDA-MB2 and MCF-7

2-amino-2-(hydroxymethyl)propane-1

IC50~3-10 µM)

30)5)55-41-36(52)38(59-39-35(51)33(49)31(47)21(3)54-39)37(29(17-46)57-41)58-40-34(50)32(48)28(16-45)56-40/h6

5-diazatricyclo[8

BACE1-IN-2 255ipexide including the breast cancer cellBACE1 IN 2 is a 1,4 Oxazine Secretase 1 (BACE1) inhibitor with an IC50 of 22 nM. Product information CAS Number: 1352416 78 4 Molecular Weight: 421. 35 Formula: C19H15F4N5O2 Chemical Name: N {3 [(2R,3R) 5 amino 3 methyl 2 (trifluoromethyl) 3,6 dihydro 2H 1,4 oxazin 3 yl] 4 fluorophenyl} 5 cyanopyridine 2 carboxamide Smiles: C[C@@]1(N=C(N)CO[C@H]1C(F)(F)F)C1=CC(=CC=C1F)NC(=O)C1=CC=C(C=N1)C#N InChiKey: YCNKUIFVRZSRNL QZTJIDSGSA N InChi: InChI=1S