NPD-1335 Catalog No.:M26121-C 1-NP also antagonized the decreases

1-NP also antagonized the decreases in responding produced by quipazine (0

by β- and γ-secretases

Smiles: NC(N)=NCCC[C@H](NC(=O)CC1(CC(=O)N2CCN(CC2)[C@@H]2C3=CC=CC=C3NC(=O)C3=CC=CC=C32)CCCC1)C(=O)NCCN1C(=O)N(C2C=CC=CC=2)N(C2C=CC=CC=2)C1=O

InChi: InChI=1S/C16H8ClF5N2O5/c17-8-5-10(19)9(18)4-7(8)13(25)24-15(28)23-11-2-1-6(14(26)27)3-12(11)29-16(20

1 or 5 μM of BVT948 for 24 h does not cause any significant changes in cell viability

NPD-1335 Catalog No.:M26121-C 1-NP also antagonized the decreasesNPD1335 is a Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death. Product information CAS Number: 2376326 31 5 Molecular Weight: 455. 55 Formula: C28H29N3O3 Chemical Name: 3 {5 [(4aS,8aR) 4 oxo 3 (propan 2 yl)